Registry Publications List

Journal Articles

  1. Yuen ST, Chung LP, Leung SY, Luk ISC, Chan SY, Ho JCI, Ho JWC, Wyllie AH.  Colorectal carcinoma in Hong Kong: epidemiology and genetic mutation. Br J Cancer 1997; 76(12): 1610-6.
  2. Leung SY, Chan TL, Chung LP, Chan ASY, Fan YW, Hung KN, Kwong WK, Ho JWC, Yuen ST. Microsatellite instability and mutation of DNA mismatch repair genes in gliomas. Am J Path 1998; 153: 1181-1188.
  3. Ho JWC, Yuen ST, Chung LP, So HC, Kwan KYM. The role of sulindac in familial adenomatous polyposis patients with ileal pouch polyposis. Aust NZ J Surg 1999 Oct; 69(10): 756-758.
  4. Chan TL, Yuen ST, Chung LP, Ho JWC, Kwan KYM, Fan YW, Chan ASY, Leung SY. Germline hMSH2 and differential somatic mutations in patients with Turcot’s syndrome. Genes Chromosomes & Cancer 1999; 25: 75-81.
  5. Yuen ST, Chan TL, Chung LP, Ho JWC, Chan SY, Ho JCY, Leung SY. Microsatellite instability and mismatch repair gene mutations are common in young colorectal cancer patients in Hong Kong. Hong Kong Med J (Suppl) 1998; 4(4): 9.2.
  6. Ho JWC, Kwan KYM, Yuen ST, Chung LP. Colonoscopic surveillance and screening for familial colorectal cancer: experience of a regional registry. Hong Kong Med J (Suppl) 1998; 4(4): 10.7.
  7. Ho JWC, Yuen ST, Chung LP, Kwan KYM. Genetic-guided screening programme for familial adenomatous polyposis: result of a regional registry.  Hong Kong Med J (Suppl) 1998; 4(4): 10.9.
  8. Chan TL, Yuen ST, Chung LP, Ho JWC, Kwan KYM, Chan ASY, Ho JCY, Leung SY, Wyllie AH. Frequent microsatellite instability and mismatch repair gene mutations in young Chinese patients with colorectal cancer. J Natl Cancer Inst 1999; Jul 21; 91(14): 1221-1226.
  9. Ho JWC, Yuen ST, Chung LP, Kwan KYM, Chang TL, Leung SY, Chan ASY, Tse CW, Lam PWY, Luk ISC. Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients. Int J Cancer (Pred Oncol) 2000; 89: 356-360.
  10. Ho JWC, Yuen ST. Screening of hereditary colorectal cancer syndrome. Asian J Surg 2000; 23: 332-343.
  11. Leung SY, Yuen ST, Chan TL, Chan ASY, Ho JWC, Kwan K, Fan YW, Hung KN, Chung LP, Wyllie AH. Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation. Oncogene 2000; 19: 4079-4083.
  12. Chan TL, Curtis LC, Leung SY, Farrington SM, Ho JWC, Chan ASY, Lam PWY, Tse CW, Dunlop MG, Wyllie AH, Yuen ST. Early-onset colorectal cancer with stable microsatellite DNA and near-diploid chromosomes. Oncogene 2001; 20: 4871-4876.
  13. Chan TL, Yuen ST, Ho JWC, Chan ASY, Kwan K, Chung LP, Lam PWY, Tse CW, Leung SY. A novel germline 1.8-kb deletion of hMLH1 mimicking alternative splicing: a founder mutation in the Chinese population. Oncogene 2001; 20: 2976-81.
  14. Andreyev HJ, Norman AR, Cunningham D, Oates J, Dix BR, Iacopetta BJ, Young J, Walsh T, Ward R, Hawkins N, Beranek M, Jandik P, Benamouzig R, Jullian E, Laurent-Puig P, Olschwang S, Muller O, Hoffmann I, Rabes HM, Zietz C, Troungos C, Valavanis C, Yuen ST, Ho JW, Croke CT, O’Donoghue DP, Giaretti W, Rapallo A, Russo A, Bazan V, Tanaka M, Omura K, Azuma T, Ohkusa T, Fujimori T, Ono Y, Pauly M, Faber C, Glaesener R, Goeij AF, Arends JW, Andersen SN, Lovig T, Breivik J, Gaudernack G, Clausen OP, Angelis PD, Meling GI, Rognum TO, Smith R, Goh HS, Font A, Rosell R, Sun XF, Zhang H, Benhattar J, Losi L, Lee JQ, Wang ST, Clarke PA, Bell S, Quirke P, Bubb VJ, Piris J, Cruickshank NR, Morton D, Fox JC, Al-Mulla F, Lees N, Hall CN, Snary D, Wilkinson K, Dillon D, Costa J, Pricolo VE, Finkelstein SD, Thebo JS, Senagore AJ, Halter SA, Wadler S, Malik S, Krtolica K, Urosevic N. Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study.  Br J Cancer 2001; 85: 692-696.
  15. Ho JWC, Chu KM, Tse CW, Yuen ST. Phenotype and management of Chinese familial adenomatous polyposis patients in Hong Kong: a Registry’s perspective.  Hong Kong Med J 2002; 8: 342-7.
  16. JHL Tsu, Ho JWC. COX-2 inhibitors and colorectal cancer chemoprevention.  Ann Coll Surg HK 2002, 6: 31-5.
  17. Davis H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Granett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt, S, Hooper St, Wilson R, Hayatilake H, Gusterson BA, Coopr C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Rgigins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JWC, Leung SY, Yuen ST, Weber BL, Seigler HF, Darro TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA.  Mutations of the BRAF gene in human cancer. Nature 2002, 417: 949-954.
  18. Yuen ST, Chan TL, Ho JWC, Chan ASY, Chung LP, Lam PWY, Tse CW, Wyllie AH, Leung SY. Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers. Oncogene 2002; 21: 7585-92.
  19. Yuen ST, Davis H, Chan TL, Ho JW, Bignell GR, Cox C, Stephens P, Edkins S, Tsue WW, Chan AS, Futreal PA, Stratton MR, Wooster R, Leung SY. Similarity of the phenotypic patterns associated with BRAF and KRAS mutations in colorectal neoplasia. Cancer Res 2002; 62: 6451-5.
  20. Ho SMY, Ho JWC, Chan CLW, Kwan K, Tsui YKY. Decisional consideration of hereditary colon cancer genetic test results among Hong Kong Chinese adults. Cancer Epidemiol Biomarkers Prev 2003; 12: 426-32.
  21. Chan TL, Chan YW, Ho JWC, Chan C, Chan ASY, Chan E, Lam PWY, Tse CW, Lee KC, Lau CW, Gwi E, Leung SY, Yuen ST. MSH2 c.1452-1455delAATG is a founder mutation and an important cause of hereditary nonpolyposis colorectal cancer in the southern Chinese population. Am J Hum Genet 2004; 74: 1035-42.
  22. Ho JWC, Ho SMY, Wong K, Chan CLW, Chan E, Yuen ST. Psychological profile of colorectal cancer genetic testing recipient in Hong Kong. Fam Cancer 2005; 4 (supp 1): 50 (F33).
  23. Ho JWC, Wei R, Chan EMS. Hereditary colorectal cancer syndromes in Hong Kong: a Registry’s perspective. Hereditary Cancer in Clinical Practice 2005; 3: 147-54.
  24. Ho JWC, Ho SMY, Ho G, Chan EMS. Psychosocial outcome of Chinese subjects undergoing genetic testing for hereditary colorectal cancer: results of a longitudinal study. Fam Cancer 2007: 6: 350(3).
  25. Tang VYH, Lee AM, Chan CLW, Leung PPY, Sham JST, Ho JWC, Cheng JYY. Disorientation and reconstruction: the meaning searching pathways of patients with colorectal cancer. J Psychosocial Oncol 2007; 25: 77-102.
  26. Tomlinson IP, Webb E, Carvajal-Carmona L, Broderick P, Howarth K, Pittman AM, Spain S, Lubb S, Walther A, Sullivan K, Jaeger E, Fielding S, Rowan A, Vijayakrishnan J, Domingo E, Chandler I, Kemp Z, Qureshi M, Farrington SM, Tenesa A, Prendergast JG, Barnetson RA, Penegar S, Barclay E, Wood W, Martin L, Gorman M, Thomas H, Peto J, Bishop DT, Gray R, Maher ER, Lucassen A, Kerr D, Evans DG, The CORGI Consortium, Schafmayer C, Buch S, Volzke H, Hampe J, Schreiber S, John U, Koessler T, Pharoah P, van Wezel T, Morreau H, Wijnen JT, Hopper JL, Southey MC, Giles GG, Severi G, Castellvi-Bel S, Ruiz-Ponte C, Carracedo A, Castells A, the EPICOLON Consortium, Forsti A, Hemminki K, Vodicka P, Naccarati A, Lipton L, Ho JW, Cheng KK, Sham PC, Luk J, Agundez JA, Ladero JM, de lay Hoya M, Caldes T, Niittymaki I, Tuupanene S, Karhu A, Aaltonen L, Cazier JB, Campbell H, Dunlop MG, Houlston RS. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 2008; 40: 623-630.
  27. Burn J, Bishop T, Mecklin JP, Macrae F, Moslein G, Olschwang S, Bisgaard ML, Ramesar R, Eccels D, Maher ER, Bertaria L, Jarvinen HJ, Lindblom A, Evans G, Lubinski J, Morrison PJ, Ho JWC, Vasen HFA, Side L, Thomas HJW, Scott RJ, Dulop M, Barker G, Elliott F, Rass  JR, Fodde R, Lynch LH, Mather JC. Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. N Engl J Med 2008; 359: 2567-78.
  28. Pittman AM, Webb E, Carvajal-Carmona L, Howarth K, Di-Bernardo M, Broderick P, Spain S, Walther A, Price A, Sullivan K, Twiss P, Fielding S, Rowan A, Jaeger E, Vijayakrishnan J, Chandler I, Penegar S, Qureshi M, Lubbe S, Domingo E, Kemp Z, Barclay E, Wood W, Martin L, Gorman M, Thomas H, Peto J, Bishop T, Gray R, Maher ER, Lucassen A, Kerr D, Evans GR; The CORGI Consortium, van Wezel T, Morreau H, Wijnen JT, Hopper JL, Southey MC, Giles GG, Severi G, Castellví-Bel S, Ruiz-Ponte C, Carracedo A, Castells A; The EPICOLON Consortium, Försti A, Hemminki K, Vodicka P, Naccarati A, Lipton L, Ho JW, Cheng KK, Sham PC, Luk J, Agúndez JA, Ladero JM, de la Hoya M, Caldés T, Niittymäki I, Tuupanen S, Karhu A, Aaltonen L, Cazier JB, Tomlinson IP, Houlston RS. Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer. Hum Mol Genet 2008; 17: 3720-7.
  29. Tomlinson IPM, Dunlop M, Campbell H, Zanke B, Gallinger S, Hudson T, Koessler T, Pharoah PD, Niittymakix I, Tuupanenx S, Aaltonen LA, Hemminki K, Lindblom A, Forsti A, Sieber O, Lipton L, van Wezel T, Morreau H, Wijnen JT, Devilee P, Matsuda K, Nakamura Y, Castellvi-Bel S, Ruiz-Ponte C, Castells A, Carracedo A, Ho JWC, Sham P, Hofstra RMW, Vodicka P, Brenner H, Hampe J, Schafmayer C, Tepel J, Schreiber S, Volzke H, Lerch MM, Schmidt CA, Buch S, Moreno V, Villanueva CM, Peterlongo P, Radice P, Echeverry MM, Velez A, Carvajal-Carmona L, Scott R, Penegar S, Broderick P, Tenesa A, Houlston RS. COGENT (Colorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. Br J Cancer 2010; 102: 447-54.
  30. Ho SMY, Ho JWC, Bonanno GA, Chu ATW, Chan EMS. Hopefulness predicts resilience after hereditary colorectal cancer genetic testing: a prospective outcome trajectories study. BMC Cancer 2010; 10: 279; doi: 10.1186/1471-2407-10-279.
  31. Ho JW, Choi AS, Lee YF, Hui TC, Cherny SS, Garcia-Barcelo MM, Carvajal-Carmona L, Liu R, To SH, Yau TK, Chung CC, Yau CC, Hui SM, Lau PY, Yuen CH, Wong YW, Ho S, Fung SS, Tomlinson IP, Houlston RS, Cheng KK, Sham PC. Replication study of SNP associations for colorectal cancer in Hong Kong Chinese. Br J Cancer 2010; doi:10.1038/sj.bjc.6605977.
  32. Houlston R and members of COGENT. COGENT (Colorectal cancer GENeTics) revisited. Mutagenesis 2012; 27: 143-51.
  33. Burn J, Gerdes AM, Macrae F, Mecklin JP, Moeslein G, Olschwang S, Eccles D, Evans G, Maher ER, Bertario L, Bisgaard ML, Dunlop MG, Ho JWC, Hodgson SV, Lindblom A, Lubinski J, Morrison P, Murday V, Ramesar R, Side L, Scot RJ, Thomas HJ, Vasen HF, Barker G, Crawford G, Elliot F, Movahedi M, Pylvanainen K, Wijnen JT, Fodde R, Lynch HT, Mathers JC, Bishop T. Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet 2011; DOI:10.1016/S0140.6736(11)61049-0.
  34. Ho SMY, Ho JWC, Paul BKY, Hui BPH, Wong RSM, Chu ATW. Hope-based intervention for individuals susceptible to colorectal cancer: a pilot study. Fam Cancer 2012; 11(4): 545-51.; doi 10.1007/s10689-012-9545-3.
  35. Mathers JC, Movahedi M, Macrae F, Mecklin JP, Moeslein G, Olschwang S, Eccles D, Evans G, Maher ER, Bertario L, Bisgaard ML, Dunlop M, Ho JW, Hodgson S, Lindblom A, Lubinski J, Morrison PJ, Murday V, Ramesar R, Side L, Scott RJ, Thomas HJ, Vasen H, Gerdes AM, Barker G, Crawford G, Elliott F, Pylvanainen K, Wijnen J, Fodde R, Lynch H, Bishop DT, Burn J, on behalf of the CAPP2 investigators.  Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet Oncol 2012; 13: 1242-49; doi 10.1016/S1470-2045(12)70475-8.
  36. Wong CY, Tang RKT, Lam RF, Io IYF, Yuen CYF, Ho JWC, Tse RKK. Muir-Torre syndrome in a middle-aged Chinese patient with sebaceous carcinoma of the eyelid. Semin Ophthalm 2013 (doi:10.3109/08820538.2013.833267).
  37. Movahedi M, Bishop DT, Macrae F, Mecklin JP, Moeslein G, Olschwang S, Eccles D, Evans DG, Maher ER, Bertario L, Bisgaard ML, Dunlop MG, Ho JW, Hodgson SV, Lindblom A, Lubinski J, Morrison PJ, Murday V, Ramesar RS, Side L, Scott RJ, Thomas HJ, Vasen HF, Burn J, Mathers JC. Obesity, Aspirin, and Risk of Colorectal Cancer in Carriers of Hereditary Colorectal Cancer: A Prospective Investigation in the CAPP2 Study. J Clin Oncol 2015 Aug 17; pii: JOC.2014.58.9952.